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  • Posted: Jan 12, 2017
    Deadline: Jan 31, 2017
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    The Biovac Institute (Biovac) is a Public Private Partnership between the South African government and the Biovac Consortium. The Biovac Institutes’ vision is to be a Centre of Excellence rooted in Africa for the development and manufacture of affordable quality vaccines for Africa and the developing world’s needs. Biovac’s focus is on ensu...
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    Senior Upstream Scientist

    Job description

    The Key Performance Areas for this position include team leadership, technical delivery, and commercial mind-set.

    • The Senior Scientist will be responsible for the overall team leadership of the Upstream Bacterial fermentation platform.
    • Lead Upstream bioprocess and fermentation product development, optimisation and technology transfer activities.
    • Develop novel upstream bioprocess and fermentation technologies with the potential for patent registration,publication and commercial value.
    • Lead Upstream development activities by:
    • Defining experimental plans and operational approaches,
    • Ensuring process data is well defined, accurate, reproducible, and within defined timelines and budgets.
    • Compilation of cGMP and GDocP quality documents.
    • Coordinate equipment installation, commissioning, performance and operator training.
    • Lead cross-departmental delivery as well as delivery to external parties.
    • Ensure compliance with respect to company safety and biosafety regulations and policies.
    • Lead and support a high performance and innovative team culture.
    • Build multi-disciplinary synergies across teams.
    • Adherence to current regulations and guidelines - both local (Medicines and Related substances Act 101  of 1965, Pharmacy Act 53 of 1974) and international.

    Candidate specifications:

    •  A PhD or MSc with at least 3 years’ experience in the relevant discipline.
    •  Advanced knowledge in the principles of microbiology, fermentation, optimization and process scaleup.
    •  Ability to lead the planning, design and execution of;  Strain development and isolate & clonal selection strategies.
    •  Fermentation (lab and pilot scale) experiments.
    •  Ability to work under biosafety level 3 containment.
    •  Strong skills in data analysis and statistics.
    •  Good presentation and technical writing skills.
    •  Sound leadership capability within multi-disciplinary teams
    •  Good decision-making skills.
    •  Ability to communicate and relate well with people at all levels.
    •  Self-starter, hands-on approach, with a drive for excellence and high standards.
    •  Ability to effectively prioritize multiple tasks and responsibilities.

    The following would be advantageous

    • Experience in cGMP Seed/ cell bank management.
    • Knowledge of cGMP (SA, PIC/S, WHO) and GLP guidelines.
    • Skills in QbD and DoE.
    • Good publication track record.

    Other requirements:

    • Local and international travel may be required.
    • Own, reliable transport required for possible standby and shift work.
    • Flexible working hours.
    The position is a long-term fixed contract position with the opportunity for permanent employment. An annual salary which is competitive in the research and development sector in SA will be negotiated relevant to experience.

    Method of Application

    Applicants should send their CV's to [email protected]

    Note:

    All positions will be filled in accordance with our Employment Equity policy as The Biovac Institute is committed to the pursuit of excellence, diversity and redress.
    Kindly note that by submitting your application for this career opportunity you agree that Biovac may use your application for the purpose of the recruitment and selection of the said position and this information may be shared with the relevant
    stakeholders in the business

    If no correspondence has been received within 3 weeks of the closing date, applicants should consider their applications unsuccessful.

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