Senior Scientist at The Biovac Institute

Job description

The Key Performance Areas for this position include

The Senior Scientist will be responsible for the overall team leadership of the Downstream Purification platform. The Senior Scientist will:

• Lead downstream purification product development, optimisation and technology transfer activities.
• Develop novel downstream bioprocess and purification technologies with the potential for patent registration, publication and commercial value.
• Lead downstream development activities by:
• Defining experimental plans and operational approaches,
• Ensuring process data is well defined, accurate, reproducible, and within defined timelines and budgets,
• Compilation of cGMP and GDocP quality documents.
• Coordinate equipment installation, commissioning, performance and operator training.
• Lead cross-departmental delivery as well as delivery to external parties.
• Ensure compliance with respect to company safety and biosafety regulations and policies.
• Lead and support a high performance and innovative team culture.
• Build multi-disciplinary synergies across teams
• Adherence to current regulations and guidelines - both local (Medicines and Related Substances Act 101 of 1965, Pharmacy Act 53 of 1974) and international.
• Candidate specifications:
• A PhD or MSc with at least 3 years’ experience in the relevant discipline.
• Advanced knowledge in the principles of chromatographic separation of complex mixtures, purification optimization and process scale-up.
• Ability to lead the planning, design and execution of;
• Streamlined purification processes using modern techniques and technologies
• Scale up and down experiments in order to establish kQA and CPP’s
• Real time and accelerated stability studies
• Ability to work under biosafety level 3 containment.
• Strong skills in data analysis and statistics.
• Good presentation and technical writing skills.
• Sound leadership capability within multi-disciplinary teams.
• Good decision-making skills.
• Ability to communicate and relate well with people at all levels.
• Self-starter, hands-on approach, with a drive for excellence and high standards.
• Ability to effectively prioritize multiple tasks and responsibilities.
• The following would be advantageous
• Knowledge of cGMP (SA, PIC/S, WHO) and GLP guidelines.
• Skills in QbD and DoE.
• Good publication track record.

Other requirements:

• Local and international travel may be required.
• Own, reliable transport required for possible standby and shift work.
• Flexible working hours.

The position is a long-term fixed contract position with the opportunity for permanent employment. An annual salary which is competitive in the research and development sector in SA will be negotiated relevant to experience.

Application deadline: 26/07/2017

All positions will be filled in accordance with our Employment Equity policy as The Biovac Institute is committed to the pursuit of excellence, diversity and redress.

Kindly note that by submitting your application for this career opportunity you agree that Biovac may use your application for the purpose of the recruitment and selection of the said position and this information may be shared with the relevant stakeholders in the business

If no correspondence has been received within 3 weeks of the closing date, applicants should consider their applications unsuccessful.