Aseptic Technician at National Bioproducts Institute

Job Advert Summary    

• Guided by its purpose to provide products for patients to alleviate pain and suffering and improve their quality of life, NBI’s vision is to be the leading African manufacturer and supplier of quality therapeutic proteins and diagnostic products.
• National Bioproducts Institute NPC has a vacancy for the role of Aseptic Technician. The successful incumbent will be required to:
• To assist with the production of sterilised products into bottles, vials and ampoules according to specifications and GMP compliance.
• To process final product till inspection as per Standard Operating Procedures and Good Manufacturing Practices.
• Applications are invited from suitably qualified and experienced candidates.

Specific SHE Requirements

• Pre-employment, routine and exit medicals are compulsory due to the nature of the business
• Attendance to SHE related training is mandatory
• Adherence to SHE Instructions
• Compliance to SHE Site Rules is compulsory
• NBI uses hazardous and biologically active chemicals.
• The successful candidate will be required to use proper PPE and will go through medical examinations as per OSH Act requirements

Specific Operational Requirements

• The successful candidate will be required to work an 8 hour shift as rostered between 06:00-18:00 or 18:00-06:00, Monday to Sunday.
• Candidate must have access to reliable transport.
• May be required to work overtime to meet the business needs.
• Must be prepared to work shifts/weekends/public holidays when needed.

Minimum Requirements    

• Grade 12 with minimum D marks in English and minimum D marks in math, science, biology or EMS
• 1-2 years experience in a pharmaceutical, chemical, biotechnology or food manufacturing environment employing GMP guidelines. 

Duties & Responsibilities    
Production of final filled products

• Preparation of equipment, machines and components by cleaning and sterilising as required
• Assembly and disassembly of machines, equipment and product transfer sets to ensure product integrity
• Operation and monitoring of all required machines and equipment
• Capping and coding of filled units
• Loading and offloading of the depyrogenation oven, autoclave, freezedryer and pasteuriser as per SOP
• Cleaning of work machinery and work areas as per SOP
• Work in the clean room and follows aseptic techniques

Sampling and environmental monitoring

• Take required samples for QC, QA and microbiology testing as required.
• Perform environmental and personnel monitoring as per SOPs
• Ensure correct labelling of samples and product samples and transfer to respective departments

Completion of batch records and auxiliary documentation

• Completes batch records timeously as required by protocols and SOPs.
• Completes log books and registers for traceability and process status records

Maintain Equipment

• Monitor equipment performance
• Works with team members to conduct first-line maintenance of equipment
• Reports incidents and machine related problems to the section head
• Assist with the calibration and validation of equipment and processes by preparing components and equipment as required.

Comply with Good Manufacturing Procedures

• Works with team members to execute SOPs and protocols to prepare, fill, freeze dry, cap and code ampoules, vials and bottles.
• Follow the gowning procedure as per SOPs and GMP requirements
• Use appropriate packaging and ensures required conditions for the appropriate storage of in-process materials and product
• Dispose of waste products according to SOP’s
• Follows the behavioural requirements for working in clean rooms
• Participates in audits of manufacturing areas
• Works with team members to assess processes and recommend methods for improving quality and efficiency
• Ensure manufacturing area is clean and tidy
• Attend training courses as required

Comply with the OHS act

• Work in a safe manner under the indirect supervision of team members.
• Wear appropriate PPE
• Act as Safety Rep, Evacuation Team Leader or First-Aider as required
• Reports any identified risks, hazards and incidents

Core Competencies

• Leading and Influencing Others
• Business Impact
• Managing Relationships
• Personal Leadership
• Attention to detail
• Oral and written communication
• Ability to work individually and in a team
• Understanding of sterile manufacturing
• Quality awareness
• Planning and Organising
• Sterile Gowning
• Clean Room Behaviour
• Automated Filling

Deadline:11th March,2026