CDC Project Manager at Novo Nordisk

• Are you passionate about delivering clinical trial excellence and ensuring high-quality execution in a complex and fast-moving environment? Do you want to play a central role in bringing innovative therapies from development to patients by leading impactful clinical projects? If so, we are looking for a driven and experienced Clinical Development Centre (CDC) Project Manager to join our team in Johannesburg, Gauteng, South Africa. This role is office based.

Your new role

• As a CDC Project Manager, you will be responsible for the end-to-end planning, coordination, and execution of assigned clinical trials within the Clinical Development Centre. You will lead cross-functional project teams, ensure delivery against timelines and budget, and uphold the highest standards of quality, compliance, and scientific rigor in accordance with ICH-GCP, regulatory requirements, and Novo Nordisk Standard Operating Procedures.

Your main responsibilities will be to:

• Lead end-to-end clinical trial delivery by planning, coordinating, and managing assigned clinical trials in line with protocols, regulatory requirements, GCP, and Novo Nordisk SOPs.
• Drive cross-functional collaboration and communication by acting as the primary interface between HQ, CDC, regional teams, investigators, and external stakeholders.
• Ensure operational excellence and compliance by overseeing trial execution quality, applying risk-based monitoring principles, and ensuring effective use of clinical systems.
• Proactively identify, manage, and mitigate project risks by setting project-specific strategies, monitoring progress against milestones, and implementing mitigation plans.
• Represent the CDC in key study forums and regulatory activities, including study meetings and investigator engagements, and ensuring timely support for local regulatory submissions.

Your new department

• You will join CDC South Africa, a vibrant and high-performing organisation dedicated to advancing clinical research and delivering world-class clinical trial execution. Based in Johannesburg, the team works in close collaboration with global and regional partners and is committed to continuous improvement, innovation, and operational excellence.

Your skills & qualifications

• Bachelor’s degree or higher in Life Sciences, Pharmacy, or a related discipline.
• GCP certification.
• 2–4 years of experience managing clinical trials, preferably multi-centre Phase II–III trials.
• Minimum of 1 year experience in Project Management
• Previous CRA experience in a commercial clinical research environment (advantageous).
• Strong knowledge of clinical trial methodology, risk-based monitoring, and GCP.
• Hands-on experience with electronic clinical trial systems (CTMS, EDC, IWRS, eTMF).
• Excellent interpersonal and communication skills.