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  • Posted: Jan 16, 2026
    Deadline: Not specified
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  • Signant Health is the evidence generation company, uniquely providing a single source for comprehensive clinical trial technology, services/support, and expertise. Trusted by researchers worldwide for more than 20 years, we transform evidence generation with industry-pioneering software solutions supported by in-house expertise in science, medicine, regulato...
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    Software Engineer - Technology R&D

    • We are strengthening our development capabilities and looking for a Software Engineer to join our growing R&D team in South Africa.

    Want to join the Best Team of Your Life?

    • We’re looking for people who are excited by the potential to make a difference in the world. You don’t need to have a clinical background to thrive at Signant. You need to be decisive, open to celebrating mistakes, able to communicate transparently and inclusively, and someone your team can count on. Most of all you need to be yourself!

    As part of our team, your main responsibilities will be to: 

    • Perform design, implementation and maintenance of product modules/sub-systems according to architecture, guidelines and good software engineering practice;
    • Take responsibility for product’s usability by creating user interfaces, creating use cases, and implementing prototypes and conducting usability tests;
    • Prepare technical documentation of product, creates user interface guidelines and conducts reviews;
    • Produce design documentation that complies with regulations;
    • Take responsibility for the unit testing and integration testing for the sprint coding;
    • Perform bug verification, release testing and support for assigned products; Researches problems discovered by Validation or Product Support and develops solutions to the problems;
    • Research and understands the marketing requirements for a product, including target environment, performance criteria and competitive issues;
    • Other responsibilities will be assigned as required.

    You’ll need to bring: 

    • M.Sc/B.Sc Degree in Computer Science, Engineering or Information Systems;
    • 3 - 5 years of software development experience;
    • Fluency in English, both written and verbal;
    • APIs: REST, GraphQL;
    • DB: RDBMS (SqlServer/Oracle / PostgreSQL and Non-RDMBS (MongoDB);
    • Monitoring: Dynatrace or similar;
    • Virtualization/Cloud: Docker, K8s;
    • AWS Secrets Management;
    • Architecture: Microservices;
    • Specific programming knowledge (1 or more);
    • Backend Java: Java (Spring), Java EE, JUnit (or similar but willing to code in JAVA/Kotlin);
    • Python (AWS python Powertools a nice to have);
    • AWS (serverless / lambda / dynamodb / SQS)
    • Terraform / Cloud Formation;
    • Build tools: Maven APIs: REST. 
    • Jenkins CICD

    Desirable:

    • User-oriented approach to software development;
    • Must be willing to expand the skills by learning other technologies as needed;
    • Must be a team-oriented person with a “can do” attitude.

    go to method of application »

    Senior Software Engineer - Technology R&D

    • We are strengthening our development capabilities and looking for a Senior Software Engineer to join our growing R&D team.

    Want to join the Best Team of Your Life?

    • We’re looking for people who are excited by the potential to make a difference in the world. You don’t need to have a clinical background to thrive at Signant. You need to be decisive, open to celebrating mistakes, able to communicate transparently and inclusively, and someone your team can count on. Most of all you need to be yourself!

    As part of our team, your main responsibilities will be to: 

    • Perform design, implementation and maintenance of product modules/sub-systems according to architecture, guidelines and good software engineering practice;
    • Take responsibility for product’s usability by creating user interfaces, creating use cases, and implementing prototypes and conducting usability tests;
    • Prepare technical documentation of product, creates user interface guidelines and conducts reviews;
    • Produce design documentation that complies with regulations;
    • Take responsibility for the unit testing and integration testing for the sprint coding;
    • Perform bug verification, release testing and support for assigned products; Researches problems discovered by Validation or Product Support and develops solutions to the problems;
    • Research and understands the marketing requirements for a product, including target environment, performance criteria and competitive issues;
    • Other responsibilities will be assigned as required.

    You’ll need to bring: 

    • M.Sc/B.Sc Degree in Computer Science, Engineering or Information Systems;
    • +7 years of software development experience;
    • Fluency in English, both written and verbal;
    • APIs: REST, GraphQL;
    • DB: RDBMS (SqlServer/Oracle / PostgreSQL and Non-RDMBS (MongoDB);
    • Monitoring: Dynatrace or similar;
    • Virtualization/Cloud: Docker, OpenShift / K8s;
    • Secrets Management (AWS Secrets Manager / Azure Keyvault / Hashicorp Vault);
    • Architecture: Microservices;
    • Specific programming knowledge (1 or more);
    • .NET – special section for SW Engineer .NET
    • Backend .NET: Microsoft Visual Studio, C#, ASP.NET, .NET Core
    • Front-End Technologies: React.JS, TypeScript, JavaScript, AJAX, CSS, XML, XSLT
    • Build tools: Azure DevOps
    • DB: Microsoft SQL Server
    • Build tools: Maven APIs: REST.

    Desirable:

    • User-oriented approach to software development;
    • Must be willing to expand the skills by learning other technologies as needed;
    • Must be a team-oriented person with a “can do” attitude.

    go to method of application »

    Clinical Scientist - Operations

    • Job Type Full Time
    • Qualification Ph.D
    • Experience 1 - 3 years
    • Location South Africa
    • Job Field Science 
    • The Clinical Scientist in the Digital Health Sciences team will provide scientific consultation to internal and external stakeholders on the use of eCOA and other digital health technologies, including eConsent and sensors and wearables, in clinical trials. The Clinical Scientist will review clinical study protocols from prospective and current customers to identify scientific and technological requirements of the clinical trial and provide advice on solution design and development. The Clinical Scientist will support pre-sales, capabilities, bid defense, requirement gathering, and design meetings. Additionally, the Clinical Scientist will provide scientific input to product development to ensure that new capabilities address the scientific requirements of future implementations, and work on marketing initiatives. The Clinical Scientist will provide consultation services through special client or internal projects and research initiatives.

    As part of our team, your main responsibilities will: 

    • Support the commercial team by analysing study protocols and other relevant study documents, documenting study requirements and presenting scientific content in client meetings.
    • Advise technical, operations, and client teams on the development of eCOA solutions to ensuring the solution design meets the clinical trial objectives.
    • Provide consultation services in the form of special projects on client-specific scientific requests or external initiatives.
    • Maintain comprehensive knowledge of the most recent industry best practices and regulatory requirements for clinical outcome assessments (COA).
    • Stay on the leading edge of eCOA and digital health technologies through participation in industry forums and working groups, and through collaboration with clients, Key Opinion Leaders.
    • Develop thought leadership materials and relevant scientific and research content to demonstrate the company’s scientific expertise internally and externally.
    • Present and promote Signant Health in the industry, including active participation in industry forums, conferences, presentations, webinars and publications on selected topics.
    • Manage time across multiple concurrent projects.
    • Develop training and marketing materials.

    DECISION MAKING AND INFLUENCE

    • Facilitates and maintains team and company culture of collegiality, respect, and professional support.
    • Considers all products and services in the context of providing the clinical trial study participant with an optimal clinical trial participation experience; identifies and drives areas for product and service improvement; provides feedback based on practice for areas of potential research; participates in patient centric research efforts.
    • Likewise considers all products and services in the context of the clinical trial research study sites.
    • Maintains Signant Health as highly regarded for scientific expertise and industry leadership.

    You’ll need to bring:

    Essential:

    • Advanced degree (PhD preferable) in Psychology.
    • 1-3 years’ solid experience in Neurology, preferably with specific expertise in Parkinson’s disease.
    • In-depth understanding of clinical research and the drug development cycle.
    • Knowledge of clinical outcome assessments (COA) and related science and/or eConsent, EDC, sensors/wearables.
    • Proven ability to multitasking, time management and task-oriented performance; able to work in a fast-paced environment.
    • Business driven and business growth savvy.
    • Familiar with the bridge between technology and science in digital health technologies for clinical trials.
    • Proven ability to be an effective, positive team player who can work across teams and in a matrix environment.
    • Ability to develop expertise in new fields through research and networking
    • Excellent knowledge of spoken and written English

    Desirable:

    • Prior experience in commercial pre-award activities, such as capabilities and bid-defense meetings, and/or solution design and requirement gathering
    • Experience in the development and use of ePRO or eCOA solutions for clinical trials
    • Can easily communicate with clients and all levels within the organization

    go to method of application »

    Senior Platform Engineer - Technology R&D

    • As a Senior Platform Engineer, you will play a pivotal role in designing, building, and maintaining the tools and infrastructure that empower our development teams and ensure business continuity. You will help drive the evolution of our Internal Developer Platform (IDP) to support seamless software delivery, scalable infrastructure, and reliable operations. This is a hands-on technical role that also requires collaboration with cross-functional teams to define strategies, solve complex problems, and enhance the developer experience.

    Want to join the Best Team of Your Life?

    • We’re looking for people who are excited by the potential to make a difference in the world. You don’t need to have a clinical background to thrive at Signant. You need to be decisive, open to celebrating mistakes, able to communicate transparently and inclusively, and someone your team can count on. Most of all you need to be yourself!

    As part of our team, your main responsibilities will: 

    Platform Development and Maintenance:

    • Design and implement features for the IDP, ensuring it aligns with our "IDP as a Product" vision.
    • Build and maintain infrastructure as code using Pulumi, Terraform, and Groovy for Jenkins.
    • Develop and maintain CI/CD pipelines to streamline deployment processes.

    Business Continuity and Operations:

    • Ensure high availability and reliability of critical tools and services such as Jenkins, Kafka, MongoDB, ArgoCD, Kubernetes (K8s), and CDN.
    • Proactively monitor, troubleshoot, and resolve platform-related issues to minimize downtime and improve performance.
    • Collaborate with CloudOps and other teams to safeguard resources and ensure alignment with best practices.

    DevOps and Automation:

    • Champion DevOps principles by implementing automation for repetitive tasks and processes.
    • Lead efforts to integrate and optimize tools such as Azure AD, Okta, Artifactory, SonarQube, Snyk, Renovate, and Backstage.

    Documentation and Enablement:

    • Contribute to and maintain comprehensive documentation for pipelines, deployment strategies, and platform features.
    • Provide guidance and support to development teams, ensuring they can fully leverage the platform's capabilities.

    Stakeholder Collaboration:

    • Work closely with engineering teams to gather requirements and design scalable solutions.
    • Participate in stakeholder meetings to present platform status, roadmap updates, and demos of new features.

    Cost Optimization and Scalability:

    • Identify opportunities for cost savings and implement solutions that improve efficiency without compromising quality.
    • Plan for future scalability of platform services as the organization grows.

    Skill Requirements:

    Technical Skills:

    • Strong expertise in Infrastructure as Code (IaC) tools: Pulumi, Terraform, and Groovy for Jenkins.
    • Advanced knowledge of Kubernetes (K8s), including cluster management and deployment strategies.
    • Proficiency in AWS and Azure AD, with a focus on scalable architecture design.
    • Experience with CI/CD tools and methodologies.
    • Familiarity with Kafka, MongoDB, and CDNs in high-performance production environments.
    • Strong programming or scripting skills (e.g., Python, Go, or Bash).
    • Experience with monitoring and observability tools, such as Incinga or similar.

    Soft Skills:

    • Exceptional problem-solving and troubleshooting abilities.
    • Strong communication skills to convey complex technical concepts to diverse audiences.
    • Collaborative mindset and experience working with cross-functional teams.
    • Ability to mentor junior team members and foster a culture of continuous improvement.

    Preferred Qualifications:

    • Demonstrated success in driving cost optimization in platform or cloud environments.
    • Familiarity with ArgoCD and Rancher.

    Method of Application

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