Research Scientist (AMR Biology) at University of Cape Town

The annual cost of employment is between R448 889-528 105.

• The Drug Discovery and Development Centre (H3D) at the University of Cape Town is seeking a Research Scientist in AMR biology for a laboratory-based position, where the primary role will be determining the in vitro efficacy of novel compounds against Gram-negative bacteria in support for H3D AMR drug discovery programs.
• The Research Scientist will report to a Senior Investigator in the AMR biology group.

Requirements:

• A minimum of a BSc Hons. degree with relevant laboratory experience in microbiology.
• Minimum 1-year hands-on experience in working with and manipulating Gram-negative bacteria (A. baumannii, K. pneumoniae and others) for a year or more is essential as demonstrated through work experience.
• Good knowledge of bacterial culturing and in vitro assessment of compound efficacy techniques.
• Experience of working in a drug discovery group is an advantage.

Responsibilities:

• Independently run routine in vitro microbiology compound efficacy experiments within a team setting.
• Be proficient in the determination of compound minimum bactericidal concentrations (MBCs), time-kill kinetic (TKK) and frequency of resistance (FoR).
• As well as bacterial strain characterization via determination of growth kinetics and antibiotic resistance profiling.
• Good knowledge of general Laboratory Health and Safety.

To apply, please e-mail the documents below in a single pdf file to [email protected].

• UCT Application Form (download at http://forms.uct.ac.za/hr201.doc)
• Cover/motivation letter
• Curriculum Vitae (CV) with at least two references, and
• Summary of previous research 

Closing date: 28 August 2026