Operator (Sterile-Eye Drops) at Adcock Ingram

Job Purpose:

• Responsible for all activities associated with the manufacturing, filling and packing operations, required to produce sterile drug products under aseptic conditions. The sterile production Operator is responsible for executing all cleanroom activities at Adcock Ingram’s Clayville manufacturing facility, while strictly adhering to cGMP, GDP, environmental health and safety guidelines, FDA regulations and any other related regulations.

Key Outputs:

• Conduct operating activities in the sterile manufacturing plant.
• Execute machine setup and change overs for the sterile eye drops machines as per SOP.
• Ensure that In-Process and Final filled product sample are taken and sent for processing.
• Execute operating procedures on PLC driven machines.
• Monitor and respond to the manufacturing particle monitoring system.
• Execute environmental monitoring operations in the sterile plant.
• Execute sterile eye drop filling machine strip down.
• Perform material cleaning, preparation and sterilization for batches.
• Monitor and respond to alarm signals from equipment.
• Execute cleanroom cleaning and sanitization procedures to ensure that facility hygiene is to the required standard.
• Participate in aseptic process validations (media fills)
• Complete production records (logbooks, MBR etc.)
• Participate in various quality system elements, including systems such as complaint handling, recall handling, deviation management, root cause analysis, CAPA management, change control, and quality risk management.
• Execute material handling activities.
• Comply with GMP requirements in the sterile plant.
• Ensure that products and components are produced handled and stored in accordance with the appropriate documentation in order to obtain the required quality.
• Follow the instructions relating to production operations including the in-process controls, and to ensure their strict implementation
• Maintain gowning competency requirements.
• Attend the required training.
• Comply with gowning requirements for sterile manufacturing

Job Requirements

• Grade 12 - Must have Life Science as a Grade 12 subject.
• N4- N6 Engineering Qualification (Mechanical, Electrical, mechatronics etc.) is an advantage but NOT a requirement. 
• Life Science post matric qualification an advantage
• At least 2 years’ experience in pharmaceutical or similar production operations
• Previous sterile/pharmaceutical or microbiological background an advantage
• Fully English literate
• Must be able to achieve a pass rate of 80% with respect to in-house sterile training requirements.

Closing Date: 27 October 2025