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  • Posted: May 15, 2026
    Deadline: May 28, 2026
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  • The Desmond Tutu Health Foundation, housed within the Desmond Tutu HIV Centre (DTHC) at the University of Cape Town, is committed to the pursuit of excellence in research, treatment, training and prevention of HIV and related infections in Southern Africa. Fully self- funded by grants and other investigator raised funds, our shared vision for the future inc...
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    Research Nurse - Phillipi Villlage

    Requirements

    • Nursing Diploma or Degree with active South African Nursing Council (SANC) registration as a Registered Nurse
    • NIMART trained
    • Sexual and reproductive health certificate (including implant insertion and removal)
    • Minimum of 2 years’ post-qualification nursing experience
    • Experience working with adolescents and young people in a clinical or community setting
    • Fluency in English and isiXhosa and/or Afrikaans
    • Computer literacy (Microsoft Office and data systems)
    • Strong verbal, written, and interpersonal communication skills
    • Ability to work under pressure and adapt to changing service delivery environments
    • Strong client-centred approach
    • Good administrative and organisational skills
    • Ability to work both independently and within a multidisciplinary team
    • High level of attention to detail
    • Valid driver’s licence
    • Willingness to travel across sites and work flexible hours, including weekends when required

    Advantageous:

    • At least one-year experience in a clinical research or implementation science environment
    • Experience in HIV prevention programmes, including PrEP delivery
    • Experience with long-acting injectable therapies
    • Dispensing certificate / Licence
    • CNP qualification
    • GCP certification
    • Experience working in community-based or mobile health services `

    Responsibilities:

    • Provide youth-friendly, integrated sexual and reproductive health (SRH) and HIV prevention services within REACH delivery platforms (facility, community, and mobile)
    • Oversee recruitment, screening, and enrolment of eligible participants in line with programme and protocol requirements
    • Manage participant care and follow-up across the full-service cascade, including retention and continuity of care
    • Conduct HIV testing and counselling in accordance with national guidelines
    • Initiate and manage oral PrEP, long-acting injectable PrEP (lenacapavir), and ART as per guidelines and protocol
    • Perform clinical assessments, including eligibility screening, adverse event monitoring, and ongoing risk assessment
    • Oversee quality control (QC) processes for HIV testing and other clinical procedures
    • Provide STI screening, treatment, and follow-up, and ensure accurate documentation in the data system
    • Deliver a range of contraceptive services and SRH interventions
    • Maintain strict client confidentiality and adhere to ethical and regulatory requirements
    • Perform required clinical procedures, including specimen collection (blood and other samples) and point-of-care testing
    • Conduct study-specific procedures in accordance with the REACH protocol and standard operating procedures (SOPs)
    • Liaise with laboratories to resolve queries and ensure accuracy of results and data
    • Ensure accurate, complete, and timely data capture using electronic case report forms (eCRFs) and relevant electronic data systems
    • Maintain high data quality through routine review, query resolution, and adherence to data management procedures
    • Perform QC checks on source documents, eCRFs, and study records
    • Ensure proper filing and maintenance of study documentation in line with GCP and audit requirements
    • Monitor participant appointments, support follow-up systems, and contribute to tracing of missed visits where required
    • Support implementation of digital tools (e.g., appointment tracking and follow-up systems) where applicable
    • Requisition medical supplies and ensure appropriate stock management and control
    • Supervise and support junior staff (e.g., HCT counsellors), including performance management and training needs identification
    • Provide ongoing mentorship and feedback to staff to improve service quality and compliance
    • Compile and contribute to monthly, quarterly, and annual programme reports
    • Participate in programme monitoring, quality improvement, and implementation activities
    • Perform any additional clinical or programme-related duties as required

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    Research Pharmacist - Phillipi Villlage

    Requirements

    • Bachelor’s degree in pharmacy with Registration with the South African Pharmacy Council (SAPC) as a pharmacist
    • At least 2 years working experience as a Research Pharmacist
    • Good Clinical Practice (GCP) certification
    • Stock management skills and experience
    • Excellent Computer literacy (Ms. Office)
    • Ability to work independently and within a team
    • Ability to use own initiative and facilitate change
    • Excellent communication skills (verbal and written)
    • Strong decision making and problem solving
    • Work Standards
    • Excellent planning and organizational skills
    • Demonstrable team player capabilities
    • Ability to interact with all stakeholders at various levels in the organization
    • Willing to work at Philippi Village Area

    Advantageous

    • Warehouse experience

    Responsibilities:

    • Pharmacy Regulatory Compliance – assist with development, implementation and maintenance of Pharmacy Standard Operating Procedures and Establishment Plans according to international regulatory standards; ensure that the pharmacy is in compliance with all applicable legislation
    • Concomitant medication management, medication is handled according to SA Pharmacy Council and SAHPRA requirements  
    • Investigational Product (IP) Management – study protocol is managed and distributed according to protocol
    • Record Management – records are accurately and timeously captured according to study protocols

    go to method of application »

    Research Nurse - Masiphumelele

    Requirements

    • A Diploma or Degree in Nursing (General or Community)
    • Active registration as a Professional Nurse with the South African Nursing Council (SANC)
    • At least 2-3 years of working experience as a Nurse
    • Knowledge of HIV and TB
    • Knowledge of study protocols / regulations
    • Excellent computer literacy with sound knowledge of email, Excel, Word processing and Internet
    • Excellent ability to build interpersonal relationships
    • Strong planning and organising ability
    • Strong verbal, written and interpersonal communication skills
    • Ability to work well under pressure and to maintain effectiveness during changing conditions
    • Ability to work harmoniously with people of diverse backgrounds and sexuality
    • Client-focused
    • Ability to work independently and as part of a team
    • Ability to foster a collaborative relationship with participants
    • Must be detail orientated
    • Strong organizational skills, including time management and multi-tasking skills
    • Administration skills
    • Maintaining strict client confidentiality
    • Preference will be given to candidates residing in or near Masiphumelele, Fish Hoek, or Muizenberg due to operational requirements
    • Valid driver’s license (Code B)

    Advantageous:

    • 1-2 year’s nursing experience in primary healthcare clinic
    • Fluency in IsiXhosa 
    • Current valid GCP certification

    Responsibilities:

    • Manage the scheduled screening, consenting, enrolment and follow-up of participants including home visits, if required
    • Participate in research studies including recruitment and enrolment, day-to-day management of study procedures, capturing data queries from monitoring
    • Working across several studies
    • Conduct all work in compliance with internationally recognized ethical and good clinical practice standards
    • Assist study coordinator in clinic functions and administrative tasks. Administrative tasks include QC of files, filing of results, calling of patients etc
    • Refer all relevant queries to study coordinator
    • Conducting phlebotomy and specimen processing
    • Perform all clinical observations and procedures as required by research protocols and on request from study coordinator (e.g. draw blood, swabs, vital signs)
    • Identify potential volunteers from database and discussion groups
    • Perform participant interviews and counselling as per protocol requirements
    • Transcribe research data into case report forms as needed
    • Inform study coordinator of daily clinic progress
    • Manage samples (or liaise with the Laboratory Technician) as per protocol requirements
    • Maintain and record cold chain temperatures
    • Assist laboratory staff with testing procedures and quality control when required
    • Ensure that all samples are collected by the respective laboratories before close of business and leaving site
    • Assist in transporting participants between clinics and research site
    • Ensure all clinical areas and equipment are maintained in good order
    • Check medical waste boxes and bins and arrange collection thereof
    • Provide participants with advice and guidance on basic medical conditions
    • Oversee participant visits and ensure participants move through all study procedures efficiently
    • Participate in conference calls, meetings and training when required
    • Assist in inventory, ordering and equipment management
    • Manage all participant reimbursements

    go to method of application »

    Clinical Project Manager

    Requirements

    • MSc in a basic biomedical science, Master of Public Health or medical degree 
    • 3- 5 years’ experience in HIV vaccine and/or HIV prevention research
    • 3- 5 years’ experience as a clinical project manager of research studies and research teams
    • Knowledge of Good Clinical Practice guidelines and clinical trial site processes is essential
    • Demonstrated leadership and people-management experience
    • Budget/grant management skills
    • Excellent ability to build interpersonal relationships and partnerships
    • Strong problem-solving and decision-making abilities
    • Excellent scientific writing and communication skills (English written and verbal)
    • High personal integrity, resilience, and attention to detail
    • Strong planning, organization and reporting skills

    Advantageous:

    • PhD in a related speciality
    • Strong research focus and a publication record
    • Experience with vaccine investigational products or immunogenicity studies
    • Experience in scientific and grant writing
    • Competence in data management, biostatistics and data interpretation
    • Familiarity with funding agency and sponsor reporting requirements

    Responsibilities:

    • Co-ordinate and oversee the implementation of an ambitious HIV vaccine programme
    • Monitoring, Evaluation and Reporting on study progress
    • Manage key project staff members ensuring deliverables are met
    • HIV vaccine trial implementation and oversight
    • Support other HIV prevention projects, including on STIs and HIV cure
    • Assist the study principal investigators and project leads with preparing reports for funders and regulators and scientific publications 
    • Maintain relationships with all key stakeholders responsible for project delivery

    Method of Application

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