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  • Posted: Jan 31, 2026
    Deadline: Not specified
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  • Signant Health is the evidence generation company, uniquely providing a single source for comprehensive clinical trial technology, services/support, and expertise. Trusted by researchers worldwide for more than 20 years, we transform evidence generation with industry-pioneering software solutions supported by in-house expertise in science, medicine, regulato...
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    Lead Cloud Operations Database Architect

    Where do you fit in?

    • We are seeking a highly experienced Lead Cloud Operations Database Architect to design, implement, and govern enterprise data architecture supporting regulated clinical research systems. This role owns all database-related aspects across Microsoft Azure and AWS cloud environments, ensuring performance, security, scalability, and compliance with GxP, FDA 21 CFR Part 11, and ICH-GCP regulations.
    • The ideal candidate brings deep technical expertise across MS SQL, Azure SQL, AWS RDS, and Cloud SQL in high-volume production environments, paired with strong leadership in data governance, architecture design, and lifecycle management for mission-critical clinical trial platforms.

    Key Responsibilities

    Architecture & Design

    • Design and maintain enterprise-scale data architectures supporting clinical trial systems
    • Ensure high availability, scalability, resilience, and security across Azure and AWS environments

    Database Administration & Operations

    • Own database setup, configuration, backup/recovery, replication, and performance tuning
    • Support MS SQL Server, Azure SQL, AWS RDS, and Cloud SQL in production environments

    Regulatory Compliance

    • Establish and enforce database procedures aligned with GxP and FDA regulations
    • Partner with QA/Compliance teams to support audits, validation, and inspections

    Security & Data Integrity

    • Implement access controls, encryption, monitoring, and logging to protect sensitive clinical and patient data

    Automation & DevOps Integration

    • Automate provisioning, patching, and schema deployments using CI/CD and IaC
    • Work with tools such as Terraform, OpenTofu, ARM templates, and AWS CloudFormation

    Cross-Functional Leadership

    • Collaborate with Engineering, Project Management, and Compliance teams to align enterprise data strategies

    Monitoring & Optimization

    • Implement proactive alerting, capacity planning, and performance optimization

    Documentation & Standards

    • Maintain architecture diagrams, SOPs, and technical documentation to support audits and validation

    You’ll need to bring

    • Bachelor’s degree in Computer Science, Information Systems, or related field (Master’s preferred)
    • 10+ years of experience in database architecture/administration
    • 5+ years of cloud experience across Azure and AWS
    • Deep expertise in MS SQL Server, Azure SQL Database, and AWS RDS
    • Proven experience supporting regulated (GxP / FDA) environments
    • Strong understanding of data security, governance, and compliance in life sciences or healthcare
    • Hands-on experience with IaC, monitoring platforms (CloudWatch, Azure Monitor), and automation scripting (PowerShell, Python, or Bash)
    • Strong communication skills and the ability to partner with cross-functional technical and clinical teams

    Nice to have

    • Experience integrating with clinical data systems (CDMS, EDC, LIMS)
    • Familiarity with Snowflake, data lakes, and ETL/ELT pipelines
    • Cloud certifications such as Azure Database Administrator or AWS Database Specialty

    Key Competencies

    • Strategic, system-level thinking
    • Strong data integrity and compliance mindset
    • Technical leadership and mentoring capability
    • Analytical problem-solving
    • Effective cross-team communication

    Check how your CV aligns with this job

    Method of Application

    Interested and qualified? Go to Signant Health on jobs.dayforcehcm.com to apply

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