Job Opportunities at South African Health Products Regulatory Authority

• Inspect different disciplines of pharmaceutical manufacturing, importing or exporting sites such as import/export/applicant and non-sterile manufacturing for compliance with Good Manufacturing Practices as accepted by SAHPRA. 
• Inspect non-sterile pharmaceutical testing laboratories (chemical and microbiological) for compliance with Good Manufacturing Practices as accepted by SAHPRA. 
• Planning of GMP inspections as per the inspection plan and travel arrangements for local, national and international inspections. 
• To work closely across inspection teams, SAHPRA programmes and external regulators to ensure inspection activities are planned and communicated effectively. 
• To adhere to the SAPRHA QMS processes

Qualification :

• Applicants must have a Matric certificate and an appropriate four-year Bachelor of Pharmacy degree or Honours Degree in Chemistry or equivalent Health Science related qualification NQF level 8 as recognised by the South African Qualifications Authority (SAQA).

Closing Date: Tuesday, 17 February 2026

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• Operational Management Ensure compliance with the provisions of the Medicine and Related Substances Act 101 of 1965 as amended, through the implementation of the strategies for preventing, detecting and responding to Substandard, Falsified, unregistered, unauthorized health products in the market.
• Key activities for this function include actively monitoring compliance with health products. 
• Import & export, Advertisements, marketing and promotions, Raid alerts and recalls, Seizures & destructions, 
• Requiring approval Sections 36 exclusions. 
• Requiring approval for Donations.

Qualification :

• Matric certificate and a four-year Bachelor of Pharmacy degree. Registration as a Pharmacist with the South African Pharmacy Council (SAPC) at NQF Level 8, as recognised by the South African Qualifications Authority (SAQA).
• A relevant Master’s qualification at NQF Level 9, as recognised by SAQA, will be an added advantage. Valid driver’s licence.

Closing Date: Thursday, 19 February 2026

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• Manage the operations of the Biological Medicines Unit concerning the processes, inputs, targets, outputs, and resourcing requirements to ensure effective operation within the unit,
• Manage the development of regulations, regulatory processes, and guidelines within the Biological Medicines Unit to ensure efficiency, considering best practice and guidelines, Compilation of statistics of the Unit to compile reports for monthly, quarterly, and annual presentations,
• Supervision of assessment and authorisation of registered and new registration applications of Biological Medicines, Management of evaluation and assessment of registration and amendments of biological medicines,
• Overseeing of vaccines and biological medicines’ Lot Release, Responsiveness to external inquiries by industry and other departments in SAHPRA and other external stakeholders...

Qualification :

• Matric certificate and appropriate four-year Bachelor’s degree in Pharmacy, Biological Sciences, Biochemistry, or Microbiology from a recognised university or tertiary institution at NQF Level 8, as recognised by the South African Qualifications Authority (SAQA),
• or an Honours degree in related health sciences at NQF Level 8 as recognised by SAQA. Registration with the South African Pharmacy Council (SAPC) is required for applicants with a BPharm degree,
• A postgraduate qualification in a relevant science such as Biochemistry, Vaccinology, Pharmacology, or equivalent, and experience in biological medicines registration will be an added advantage.

Closing Date: Friday, 20 February 2026

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• Develop strategy, annual performance plan, operational plans, and budget for the Medical Device and Radiation Control Programme, aligned with organisational needs and optimal resource utilisation,
• Direct regulation of medical devices (including medical and industrial radiation-emitting devices), radionuclides, and electronic generation of ionizing and non-ionizing radiation,
• Oversee development, implementation, and maintenance of regulations, guidelines, policies, and procedures aligned with international/national protocols and legislation,
• Oversee effective, timeous communication and consultation on issues related to medical devices, radiation-emitting devices, radionuclides, and radiation generation, Build sustainable partnerships with public and private sectors to deliver SAHPRA programmes,
• Oversee programme budget, implement cost-saving measures in line with PFMA and Treasury regulations, and handle general financial responsibilities...

Qualification :

• A Matric certificate and an appropriate Master’s degree in Biomedical Engineering, Clinical Engineering, Medical Physics, or a related equivalent qualification at NQF Level 9, as recognised by the South African Qualifications Authority (SAQA).
• A management qualification such as a Master of Business Administration (MBA), Master of Business Leadership (MBL), or a Management Advancement Programme (MAP) will be an added advantage.

Closing Date: Friday, 20 February 2026

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• Evaluation and assessment of the quality, safety and efficacy of new applications for the registration Biological Medicines,
• Evaluation and assessment of applications for the amendment of the quality, safety and efficacy aspects of registered Biological Medicines,
• Evaluating applicant responses and variations for registrations and/or approval of Biological medicines,
• Develop and update guidelines and/or SOPs as required, Participate in pre-registration consultations with manufacture, Lot release functions for Vaccines...

Qualification :

• Matric certificate and a relevant four-year Bachelor of Pharmacy, Biological Sciences, Biochemistry or Microbiology degree from a recognised university or tertiary institution at NQF Level 8 as recognised by the South African Qualifications Authority (SAQA) or
• an Honours degree in related health sciences at NQF Level 8 as recognised by SAQA. (Registration with the South African Pharmacy Council (SAPC) is a requirement with a BPharm degree.
• A postgraduate qualification in relevant Science such as Biochemistry, Vaccinology, Pharmacology or equivalent and experience in biological medicines registration is an added advantage.

Closing Date: Friday, 20 February 2026

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• Evaluate and generate evaluation report(s) for registration applications (Generics & New Chemical Entities) in compliance with required template and adopted regulatory /scientific standards (SAHPRA and VICH/EMA technical requirements) and submit for peer review,
• Evaluate and generate evaluation report(s) for clinical variation applications (Generics & NCEs) in compliance with required template and adopted regulatory /scientific standards (SAHPRA and VICH/EMA guidelines) and submit for peer review, Provide quality assurance of reports and facilitate resolutions on technical matters, Develop and update guidelines, and templates,
• Form part of technical working groups or special projects and provide support to the unit as well as to advisory committees, Adhere to SOPs and guidelines..

Qualification :

• Matric certificate and a Bachelor of Veterinary Science degree at NQF Level 8, as recognized by the South African Qualifications Authority (SAQA).
• Additionally, candidates must be registered in South Africa to practice as a veterinarian. A postgraduate qualification will be considered an advantage.

Closing Date: Friday, 20 February 2026

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• Evaluation and assessment of the quality, safety and efficacy of new applications for the registration of Biological Medicines,
• Evaluation and assessment of applications for the amendment of the quality, safety and efficacy aspects of registered Biological Medicines,
• Evaluating applicant responses and variations for registrations and/or approval of medicines, Conducting Pre-Registration Consultation meeting for Biological Medicines,
• Develop and update guidelines and/or SOPs as required, Participate in pre-registration consultations with manufacture.

Qualification :

• Matric certificate and a relevant four-year Bachelor’s degree in Pharmacy, Biological Sciences, Biochemistry, or Microbiology from a recognized university or tertiary institution at NQF Level 8, as acknowledged by the South African Qualifications Authority (SAQA).
• Alternatively, an Honours degree in a related health science at NQF Level 8, also recognized by SAQA, is acceptable.
• For those with a Bachelor of Pharmacy (BPharm) degree, registration with the South African Pharmacy Council (SAPC) is mandatory, and proof of active registration as a Pharmacist must accompany the application.

Closing Date: Friday, 20 February 2026

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• Reviewing a broad range of applications as a primary-, peer reviewer.
• Conducts evidence-informed practice.
• Makes or recommends regulatory decisions.

Qualification :

• Matric certificate and an appropriate four-year degree in Pharmacy at NQF Level 8 as recognised by the South African Qualifications Authority (SAQA) and registration with a Professional Body (South African Pharmacy Council) or an MBChB degree and registration as a Medical Officer with the Health Professions Council of South Africa (HPCSA).
• A relevant Masters degree in Health Sciences will be an added advantage.

Closing Date: Monday, 23 February 2026

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• Plan and perform inspections in accordance with the Hazardous Substances Act, related regulations and code of practice, Prepare formal reports of your finding/s during inspections,
• Participate in inspection activities involving high-risk electronic generators of ionising radiation, such as linear accelerators, cyclotrons, industrial radiography etc,
• Verification of quality control tests from licence holders’ equipment as prescribed by national standards, Receive and investigate incidents and accidents as reported by licence holders,
• Receive and investigate occupational radiation overexposures from licence holders as supplied by approved dosimetry laboratories,
• Developing and implementing of guidelines, code of conducts and standard operating procedures, Receive and respond to various queries received by the subunit in accordance with query management standard procedure.

Qualification :

• Matric certificate plus a BSc Hons Medical Physics
• Professional registration with HPCSA
• Valid driver’s licence is essential.

Closing Date: Friday, 27 February 2026